A long-standing dogma in plant disease susceptibility states that disease development requires not only the presence of a virulent pathogen and a susceptible host but also a set of disease-favoring environmental conditions. How environmental conditions influence the plant and the pathogen during an active interaction is poorly understood, leaving a big gap in our understanding of how disease outbreaks occur in nature. To gain insight into the molecular basis of the “disease triangle” dogma, our lab is interested in research projects to elucidate how suboptimal environmental factors intercept the molecular network associated with disease development under global climate change, becoming a serious concern for humankind.

식물-미생물-환경 상호작용 연구실 (Lab of Plant-Microbe-Environment Interactions; PMEI)은 외부 환경로 인해 식물-미생물의 상호작용이 어떻게 조절되는지를 개체 및 분자 수준에서 연구합니다.
식물병리학의 병삼각형 (Disease triangle)은 기주식물, 병원체와 더불어 환경적인 요인이 식물병의 발생에서 중요한 요소라는 것을 강조하고 있습니다. 그러나 이전의 분자식물병리학 연구들은 기주식물과 병원체의 상호작용에 초점을 맞추어 진행되었고, 그렇기 때문에 식물-미생물 상호작용에서 환경이 주는 변화에 대한 연구가 필요합니다. 특히 변화하는 기후로 인하여 식물병이 증가하고 있는 상황에서 우리 연구실은 식물-미생물 상호작용 속 분자적 변화를 규명하려고 합니다.

학사연구논문을 위해 학생들은 아래의 주제와 관련된 소규모 프로젝트를 수행할 수 있습니다.

- 모델 식물 애기장대 돌연변이체 제작을 위한 분자생물학 실험
- 모델 식물 애기장대 야생형 및 돌연변이체의 여러가지 환경 조건 (예: 고온, 고습)에서의 병징 (Symptom) 변화 조사 및 유전자 발현, 파이토호르몬 변화 분석
- 저온 곡물의 모델 식물인 Brachypodium, 저온 곡물 작물인 밀의 여러가지 환경 조건 (예: 고온, 고습)에서의 병징 (Symptom) 변화 조사 및 유전자 발현, 파이토호르몬 변화 분석

• ㆍUnderstanding the effect of suboptimal environmental conditions on plant-microbe interactions from the view of plant physiology to the molecular level
• ㆍDesigning climate-resilient crop plants through genome-editing methods

• ㆍChen J, Li L, Kim JH, Neuhäuser B et al., (2023) Small proteins modulate the activity of the Arabidopsis thaliana ion channel-like immune regulator ACD6. Molecular Cell 83:1-12
• ㆍKim JH, Castroverde CDM et al., (2022) Increasing the resilience of plant immunity to a warming climate. Nature 607:339-344
• ㆍKim JH, Oh TR et al., (2019) Inverse correlation between MSPR1 and AtHSP90.1 balances the cytoplasmic PQC process in Arabidopsis. Plant Physiol 180(2):1230-1240
• ㆍKim JH, Cho SK et al., (2017) MPSR1 is a novel cytoplasmic PQC E3 ligase for eliminating emergent misfolded proteins in Arabidopsis thaliana. Proc Natl Acad Sci U S A 114(46): 10009–E10017
• ㆍOh TR, Kim JH et al., (2017) AtAIRP2, an Arabidopsis RING E3 Ubiquitin Ligase, Positively Regulates ABA-mediated Seed Germination and Salt Stress Response in Early Seedlings by Stimulating ATP1/SDIRIP1 Turnover. Plant Physiol 174: 2515-2531
• ㆍKim JH and Kim WT, The Arabidopsis RING E3 Ubiquitin Ligase AtAIRP3/LOG2 Participates in Positive Regulation of High-Salt and Drought Stress Responses. (2013) Plant Physiol 3: 1733-1749

• ㆍB.S., Yonsei University, Korea (2010)
• ㆍPh.D., Yonsei University, Korea (2017)

• ㆍ2017-2018 : Postdoc. Associate, Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea (Advisor: Dr. Woo Taek Kim)
• ㆍ2018-2019 : KRF Postdoc. Fellow (Korea Research Foundation Postdoc. Fellowship), DOE Plant Research Laboratory, Michigan State University, East Lansing, United States (Advisor: Dr. Sheng Yang He)
• ㆍ2019-2020 : Research Specialist, Howard Hughes Medical Institute, DOE Plant Research Laboratory, Michigan State University, United States (Advisor: Dr. Sheng Yang He)
• ㆍ2020-2023 : Research Specialist, Howard Hughes Medical Institute, Duke University, United States (Advisor: Dr. Sheng Yang He)
• ㆍ2023-Present : Assistant professor, POSTECH, Pohang, South Korea

• ㆍPostdoctoral Fellowship Program in 2018 granted by National Research Foundation of Korea (NRF) (2018)