We are developing computational biology methods and bioinformatics tools for network medicine and healthcare. Proteins are the major player of cellular function and they carry out their functional role through complex network of protein-protein interactions.
The protein repertoire varies depending on cellular states, tissue type, species, and disease state. However, little is known about how this repertoire changes under different cellular or disease states. To gain a better understanding of these dynamic changes, Kim's lab is developing essential applications for network biology and large-scale high-throughput data integration analysis.
Systemic analysis of protein functional network will provide a framework for understanding how protein compositions respond to changes in human disease states.