In the Laboratory of Tissue Regeneration and Development, we are dedicated to unraveling the intricate dynamics of tissue repair and development, employing mouse skin and embryos as our model systems. Our research initiatives delve into the complexities of wound healing process and the sophisticated landscape of tissue development, including embryonic growth.
At the core of our investigations lies a comprehensive exploration of the roles played by stem cells, emphasizing their intercellular communication within the tissue microenvironment, occurring in diverse forms, including extracellular vesicles. Navigating the elaborate system of cellular communication, differentiation, and regeneration, our objective is to elucidate the underlying mechanisms governing these processes. Ultimately, our goal is to provide innovative therapeutic strategies that advance regenerative medicine and effectively address tissue-related disorders.

Tissue repair and regeneration
• ㆍStem cell biology
• ㆍIntercellular communication & Extracellular vesicles
• ㆍAging

Tissue development
• ㆍEmbryonic development
• ㆍCellular senescence

[ Research topics ]
• ㆍInvestigating the interaction between tissue-resident stem cells and their microenvironment during the process of skin wound healing.
• ㆍExploring the roles played by intercellular communication via extracellular vesicles (i.e. microvesicles and exosomes) in the wound healing process.
• ㆍStudying the effects of aging-induced changes in stem cells on delayed wound healing.
• ㆍUnraveling the mechanisms and significance of intercellular communication during mammalian embryonic development.
• ㆍUnderstanding the contributions of cellular senescence to wound healing and embryonic development.

• ㆍLiu S and Hur YH et al. (2023), A tissue injury sensing and repair pathway distinct from host pathogen defense. Cell 186, 1-17.
• ㆍHur YH et al. (2021), Embryonic stem cell-derived extracellular vesicles maintain ESC stemness by activating FAK. Developmental Cell 56, 277–291.
• ㆍHur YH et al. (2020), Extracellular vesicles and their roles in stem cell biology. Stem Cells 38, 469–476.

• ㆍD.V.M., Seoul National University (2016) : Graduated as the top student with the highest GPA from the College.
• ㆍPh.D., Cornell University (2021)

• ㆍ2021-2024 : Postdoctoral Fellow (AACR Immuno-oncology fellow), Laboratory of Mammalian Cell Biology and Development, The Rockefeller University
• ㆍ2024-Present : Assistant Professor, Department of Life Sciences, POSTECH

• ㆍ2017 Cornell Biomedical & Biological Sciences Symposium Runner-up Poster Presentation Award (2017)
• ㆍ2018 Cornell Biomedical & Biological Sciences Symposium Poster Presentation Award (2018)
• ㆍCornell Biomedical & Biological Sciences Three Minute Thesis (3MT) Presentation Award (2020)
• ㆍAACR-Incyte Immuno-oncology Postdoctoral Research Fellowship (2022-2024)
• ㆍSUNY Chancellor’s Distinguished Dissertation Award finalist (2022)
• ㆍ2022 Stem Cell Research Annual Meeting, Global young scientist award; runner-up (2022) (2023)
• ㆍ2023 KASBP-Dong-A-ST Fall Fellowship (2023)